Thermo Fisher Scientific CD20 Monoclonal Antibody (LT20)
CD20 항원을 인식하는 Mouse IgG2a 단일클론 항체로, 인간 B 세포 표면 단백질 분석에 적합합니다. IHC 및 유세포 분석에 사용 가능하며, Protein A 정제 및 PBS 완충액에 보관됩니다. 연구용으로만 사용 가능합니다.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Immunohistochemistry (IHC) | - | View 1 publication |
| Flow Cytometry (Flow) | 3 µg/mL | View reference |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | LT20 |
| Immunogen | Normal human lymphocytes from lymph node |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 15 mM sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_1071535 |
Additional Formats
Product Specific Information
This antibody reacts with an extracellular epitope of CD20 (Bp35), a 33–37 kDa non-glycosylated membrane receptor with four transmembrane domains. CD20 is expressed on B lymphocytes (but lost on plasma cells), follicular dendritic cells, and at low levels on peripheral blood T lymphocytes.
Target Information
CD20 is a non-glycosylated surface phosphoprotein (33–37 kDa) expressed on mature and most malignant B cells, a subpopulation of T lymphocytes, and follicular dendritic cells. It regulates transmembrane calcium conductance, cell cycle progression, and B-cell proliferation. CD20 is associated with lipid rafts, and its expression makes it a useful target for antibody-mediated therapeutic depletion of B cells. Diseases associated with CD20 dysfunction include Ms4a1-related common variable immune deficiency.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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배송/결제/교환/반품 안내
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