Thermo Fisher Scientific ZDHHC16 Polyclonal Antibody
ZDHHC16 단백질을 인식하는 Rabbit Polyclonal 항체로 Human, Mouse, Rat 시료에 반응합니다. WB, IHC, ICC, ELISA 등 다양한 응용에 적합하며 Protein A로 정제되었습니다. -20°C에서 보관하며 연구용으로 사용됩니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:300–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | Assay-dependent |
| Immunohistochemistry (Frozen) (IHC-F) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Detail |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH-conjugated synthetic peptide derived from human ZDHHC16 (amino acids 271–377) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
ZDHHC16 (zinc finger, DHHC-type containing 16), also known as APH2, is a 377 amino acid multi-pass membrane protein localized to the endoplasmic reticulum and containing one DHHC-type zinc finger. It exists as multiple alternatively spliced isoforms, interacts with c-Abl, and catalyzes the conversion of Palmitoyl-CoA and protein-cysteine to S-palmitoyl protein and CoA. Through its association with c-Abl, ZDHHC16 may play a role in apoptosis regulation.
The ZDHHC16 gene maps to human chromosome 10, which contains over 1,200 genes and accounts for approximately 4.5% of the human genome. Mutations in genes located on chromosome 10 are linked to disorders such as Charcot-Marie-Tooth disease, Jackson-Weiss syndrome, Usher syndrome, nonsyndromic deafness, Wolman’s syndrome, Cowden syndrome, multiple endocrine neoplasia type 2, and porphyria.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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