Thermo Fisher Scientific ZDHHC16 Polyclonal Antibody

Applications and Tested Dilutions

Product Specifications

Target Information

ZDHHC16 (zinc finger, DHHC-type containing 16), also known as APH2, is a 377 amino acid multi-pass membrane protein localized to the endoplasmic reticulum and containing one DHHC-type zinc finger. It exists as multiple alternatively spliced isoforms, interacts with c-Abl, and catalyzes the conversion of Palmitoyl-CoA and protein-cysteine to S-palmitoyl protein and CoA. Through its association with c-Abl, ZDHHC16 may play a role in apoptosis regulation.

The ZDHHC16 gene maps to human chromosome 10, which contains over 1,200 genes and accounts for approximately 4.5% of the human genome. Mutations in genes located on chromosome 10 are linked to disorders such as Charcot-Marie-Tooth disease, Jackson-Weiss syndrome, Usher syndrome, nonsyndromic deafness, Wolman’s syndrome, Cowden syndrome, multiple endocrine neoplasia type 2, and porphyria.

For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.