Thermo Fisher Scientific TOP2A Polyclonal Antibody
TOP2A 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot, IHC, ICC 등 다양한 응용에 적합. 인간에 반응하며, 단백질 합성 및 세포 분열 연구에 활용 가능. 고순도의 Protein A 및 항원 친화 정제 방식으로 제조.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:100 |
| Immunocytochemistry (ICC/IF) | 1:10–1:50 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide between amino acids 1167–1196 from the C-terminal region of human TOP2A |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A, Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2543755 |
Product Specific Information
This antibody is predicted to react with hamster, mouse, and rat based on sequence homology.
Target Information
Topo II alpha plays important roles in DNA synthesis and transcription as well as chromosomal segregation during mitosis. It is a sensitive and specific marker of late S-, G2-, and M-phases in transformed and developmentally regulated normal cells. Topo II alpha is also implicated in drug resistance of tumor cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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