Thermo Fisher Scientific CD4 Monoclonal Antibody (SK3 (SK-3)), Brilliant Ultra Violet 395, eBioscience

Applications

• Flow Cytometry (Flow): 5 µL (0.25 µg)/test

Product Specifications

Additional Available Formats

• Alexa Fluor 532, Alexa Fluor 700, APC, APC-eFluor 780
• Brilliant UV 496, 563, 737, 805
• Brilliant Violet 421, 605
• eFluor 450, FITC
• NovaFluor Blue, Red, Violet, Yellow 시리즈
• PE, PE-Cyanine5.5, PE-Cyanine7, PE-eFluor 610
• PerCP-eFluor 710, Super Bright 시리즈
• Request custom conjugation

Product Specific Information

The SK3 monoclonal antibody reacts with human CD4, a 59-kDa surface receptor expressed on most thymocytes, a subset of mature T helper cells, and at low levels on monocytes. CD4 serves as a receptor for HIV, and SK3 blocks HIV binding and mixed lymphocyte reaction. SK3 and RPA-T4 recognize distinct epitopes.

• Applications Reported: Flow cytometric analysis
• Applications Tested: Pre-diluted and tested for normal human peripheral blood cells. Recommended use: 5 µL (0.25 µg) per test in 100 µL final volume.
• Fluorochrome: Brilliant Ultra Violet™ 395 (BUV395), excitation at 350 nm, emission at 395 nm.
• Laser: Ultraviolet (355 nm)

When using multiple polymer dye-conjugated antibodies, use Super Bright Complete Staining Buffer (Product # SB-4401-42) or Brilliant Stain Buffer™ (Product # 00-4409-75) to minimize non-specific interactions.

Trademark Notice: BRILLIANT ULTRA VIOLET™ is a trademark of Becton, Dickinson and Company or its affiliates, used under license. Powered by Sirigen™.

Target Information

CD4 antigen is involved in recognition of MHC class II molecules and acts as a co-receptor for HIV. It is primarily expressed in T helper cells and other immune cells such as monocytes, macrophages, and dendritic cells. CD4 expression is found in thymus, lymph nodes, tonsils, spleen, and certain non-lymphoid tissues. It plays a key role in T-cell activation and may mediate neuronal damage in infectious or immune-mediated CNS diseases.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without authorization.

제품 이미지