
Thermo Fisher Scientific Mouse CCL22 (MDC) Recombinant Protein
Mouse CCL22(MDC) 재조합 단백질로, 활성 T-림프구 및 수지상세포의 화학주성 연구에 적합. E. coli 발현, >98% 순도, ED50 1–30 ng/mL. Lyophilized 형태로 -20°C 보관. 연구용으로만 사용.
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- Protein
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Applications
- Western Blot (WB): Assay-dependent
- Immunohistochemistry (IHC): Assay-dependent
- ELISA (ELISA): Assay-dependent
- Functional Assay: Assay-dependent
- Control (Ctrl): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species | Mouse |
| Expression System | E. coli |
| Amino Acid Sequence | Mouse CCL22 recombinant protein contains 68 amino acids |
| Molecular Weight | 7.8 kDa |
| Class | Recombinant |
| Type | Protein |
| Purity | >98% by SDS-PAGE |
| Endotoxin Concentration | <0.1 ng/µg |
| Activity | ED50 = 1–30 ng/mL (dose-dependent chemotaxis of mouse BW5147.3 cells) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Purification | Purified |
| Contains | No preservative |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
Product Specific Information
Reconstitution:
Before opening, briefly centrifuge the vial to bring contents to the bottom.
Reconstitute MDC in sterile, distilled water to 0.1–1.0 mg/mL.
Further dilutions should be made in aqueous buffers supplemented with carrier protein (e.g., 0.1–1.0% BSA).
Storage:
Lyophilized preparation is stable at 2–8°C, but store at -20°C for long-term storage (preferably desiccated).
After reconstitution, stable for up to one week at 2–8°C.
For maximal stability, aliquot and store at -20°C.
Avoid repeated freeze/thaw cycles.
Target Information
CCL22 may play a role in the trafficking of activated/effector T-lymphocytes to inflammatory sites and other aspects of activated T-lymphocyte physiology.
It is chemotactic for monocytes, dendritic cells, and natural killer cells.
CCL22 acts as a mild chemoattractant for primary activated T-lymphocytes and a potent chemoattractant for chronically activated T-lymphocytes.
No chemoattractant activity for neutrophils, eosinophils, or resting T-lymphocytes.
Binds to CCR4.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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