Thermo Fisher Scientific Phospho-PDX1 (Thr11) Polyclonal Antibody
Human PDX1 인산화(Thr11) 부위를 인식하는 Rabbit Polyclonal Antibody로, Western blot 및 Dot blot에 사용 가능. Protein A 및 항원 친화 크로마토그래피로 정제됨. PBS 버퍼에 보존되며, 4°C 단기 또는 -20°C 장기 보관 가능.
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Applications
Western Blot (WB)
- Tested Dilution: Not specified
- View 1 publication
Dot Blot (DB)
- Tested Dilution: 1:500
- View publication
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding T11 of human PDX1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Protein A, Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_10985921 |
Product Specific Information
This antibody is predicted to react with mouse and rat based on sequence homology.
Target Information
The protein encoded by this gene is a transcriptional activator of several genes, including insulin, somatostatin, glucokinase, islet amyloid polypeptide, and glucose transporter type 2.
It is involved in early pancreatic development and plays a major role in glucose-dependent regulation of insulin gene expression.
Defects in this gene can cause pancreatic agenesis, leading to early-onset insulin-dependent diabetes mellitus (NIDDM) and maturity onset diabetes of the young type 4 (MODY4).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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