Thermo Fisher Scientific IL-34 Polyclonal Antibody
IL-34 단백질을 인식하는 Rabbit Polyclonal 항체로, Human, Mouse, Rat 시료에 반응합니다. Western blot에 최적화되어 있으며, 항원 친화 정제 방식으로 제조되었습니다. PBS 버퍼에 0.02% sodium azide가 포함되어 있으며, 냉장 또는 장기 보관 시 -20°C에서 안정적으로 유지됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.25 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A 13 amino acid peptide from near the center of human IL-34 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | Maintain refrigerated at 2–8°C for up to 3 months. For long-term storage, store at -20°C. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11155028 |
Product Specific Information
Despite its predicted molecular weight, IL-34 often migrates at a higher molecular weight in SDS-PAGE.
A suggested positive control is human brain tissue lysate.
PA5-20594 can be used with blocking peptide PEP-0714.
Target Information
IL-34 is secreted as a dimeric protein and currently belongs to no known cytokine family. It signals via the M-CSF Receptor (CSF-1R, CD115), which is shared with M-CSF.
Although IL-34 has no amino acid sequence homology to M-CSF, they exhibit similarities in secondary structure and share overlapping functions.
IL-34 has been shown to promote myeloid survival, proliferation, and differentiation, and to play a role in osteoclast formation.
IL-34 expression has been detected in various tissues and is most abundant in the spleen.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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