Thermo Fisher Scientific Calpain 6 Polyclonal Antibody
Calpain 6 단백질을 인식하는 Rabbit Polyclonal 항체로, WB, IHC, ICC/IF에 사용 가능. Human, Mouse, Rat 시료에 반응하며, 단백질 A로 정제된 액상 형태. 2–8°C 보관, 장기 보관 시 -20°C 권장. 연구용으로만 사용.
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific Calpain 6 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.5–1 µg/mL |
| Immunohistochemistry (IHC) | 2.5 µg/mL |
| Immunocytochemistry (ICC/IF) | 20 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | An 18 amino acid peptide from near the carboxy terminus of human CAPN6 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | Maintain refrigerated at 2–8°C for up to 3 months. For long term storage, store at -20°C. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11154625 |
Product Specific Information
- A suggested positive control is rat lung tissue lysate.
- PA5-20592 can be used with blocking peptide PEP-0712.
Target Information
Calpain-6 (also known as calpamodulin or calpain-X) is an intracellular, calcium-dependent cysteine protease. It shows tissue-specific expression in adults, mainly in the placenta, and embryonically in several tissues.
Classical calpains consist of a common small subunit (calpain-4) and a large variable subunit, but it is not known if calpain-6 associates with a small subunit. The large subunit includes domain-I (amino terminal), domain-II (proteinase), domain-III, and domain-IV (EF-hand domain).
Calpain-6, located on the X chromosome, lacks the EF-hand calcium-binding motif found in domain-IV of classical calpains. The active site residues Cys, His, and Asn are replaced by Lys, His, and Asn in human, and Lys, Tyr, and Asn in mouse calpain-6, suggesting that it is unlikely to be proteolytically active.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.