Thermo Fisher Scientific GluR6/GluR7 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

-

View 1 publication 1 publication

Immunohistochemistry (Paraffin) (IHC (P))

1:100

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Product Specifications

Published species

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Synthetic peptide from C-terminus of human GluR6/7. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:GluR6/GluR7,uniProtId:Q13002-1,ncbiNodeId:9606,antigenRange:908,antigenLength:908,antigenImageFileName:PA1-37780_GluR6GluR7_Q13002-1_Rabbit.svg,antigenImageFileNamePDP:PA1-37780_GluR6GluR7_Q13002-1_Rabbit_PDP.jpeg,sortOrder:1},{targetFamily:GluR6/GluR7,uniProtId:Q13003-1,ncbiNodeId:9606,antigenRange:919,antigenLength:919,antigenImageFileName:PA1-37780_GluR6GluR7_Q13003-1_Rabbit.svg,antigenImageFileNamePDP:PA1-37780_GluR6GluR7_Q13003-1_Rabbit_PDP.jpeg,sortOrder:2}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2116317

Product Specific Information

This antibody is predicted to react with bovine, chicken, canine, amphibian, mouse, rabbit and rat based on sequence homology.

Heat-mediated antigen retrieval is recommended prior to staining, using a 10mM citrate buffer, pH 6.0, for 10 minutes followed by cooling at room temperature for 20 min. Following antigen retrieval, incubate samples with primary antibody for 30 min at room temperature. A suggested positive control is brain tissue.

Target Information

Glutamate receptors constitute the principal excitatory neurotransmitter receptors in brain. Two classes of glutamate receptors exist: ionotropic receptors, and metabotropic receptors. Ionotropic glutamate receptors are oligomeric complexes of various subunits (GluR1-7, NMDA1-3, KAI-2), which comprise ligand-gated calcium channels. Metabotropic glutamate receptors are G-protein coupled receptors, which when activated can activate phopholipases or adenylylcyclase, depending on the neuron.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.