Thermo Fisher Scientific SARS-CoV-2 Spike Protein (RBD) Polyclonal Antibody
SARS-CoV-2 Spike Protein RBD에 특이적인 Rabbit Polyclonal Antibody. Western blot, IHC, ICC, Flow Cytometry, ELISA 등 다양한 응용 가능. SARS-CoV 및 MERS-CoV와 교차 반응 없음. 항원 친화 크로마토그래피로 정제된 고품질 항체.
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Thermo Fisher Scientific SARS-CoV-2 Spike Protein (RBD) Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:1,000–1:10,000 | View 3 publications |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent | - |
| Immunocytochemistry (ICC/IF) | Assay-dependent | - |
| Flow Cytometry (Flow) | Assay-dependent | View 1 publication |
| ELISA | Assay-dependent | - |
| Immunoprecipitation (IP) | - | View 1 publication |
| Neutralization (Neu) | Assay-dependent | - |
| Inhibition Assays (IA) | Assay-dependent | - |
Product Specifications
| Specification | Detail |
|---|---|
| Species Reactivity | Virus |
| Published Species | Dog, Human, Non-human primate, Virus |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to SARS-CoV-2 (COVID-19) Spike RBD |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 20% glycerol |
| Contains | 0.025% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2890581 |
Product Specific Information
This antibody detects SARS-CoV-2 Spike protein but does not cross-react with SARS-CoV or MERS-CoV spike proteins based on internal testing.
Target Information
SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2), also known as 2019-nCoV, causes illnesses ranging from mild cold symptoms to severe respiratory distress and death. The Spike (S) protein is crucial for viral attachment, fusion, and entry, making it a key target for antibody, inhibitor, and vaccine development.
The receptor-binding domain (RBD) of the Spike protein binds strongly to human and bat ACE2 receptors, exhibiting higher affinity than SARS-CoV RBD. The S1 subunit contains the RBD responsible for specific ACE2 binding on target cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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