Thermo Fisher Scientific LKB1 Monoclonal Antibody (E.425.6)
LKB1 단백질을 인식하는 Thermo Fisher Scientific의 단일클론 항체. Western blot에 적합하며 인간, 마우스, 원숭이, 랫트 시료에서 반응. 고순도 친화 크로마토그래피 정제, 액상 형태로 제공. 연구용으로만 사용 가능.
- 판매단위
- pk
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Applications
- Western Blot (WB): 1:1,000 dilution
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Non-human primate, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Monoclonal |
| Type | Antibody |
| Clone | E.425.6 |
| Immunogen | An LKB1 partial fusion protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 24 µg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | 0.01M HEPES (pH 7.5), 0.15M NaCl, 100 µg/mL BSA, 50% glycerol |
| Contains | <0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_10983345 |
Product Specific Information
It is not recommended to aliquot this antibody.
Target Information
LKB1 (also known as STK11, Serine/threonine-protein kinase STK11) is a tumor suppressor belonging to the serine/threonine kinase family.
LKB1 physically associates with p53 and regulates specific p53-dependent apoptosis pathways.
It is present in both the cytoplasm and nucleus and translocates to mitochondria during apoptosis.
LKB1 acts as a master upstream kinase, regulating AMPK and AMPK-related kinases.
Mutations in the LKB1 gene are associated with Peutz-Jeghers syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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