
Thermo Fisher Scientific Relaxin 1 Polyclonal Antibody, Biotin
Biotin으로 표지된 Relaxin 1 폴리클로날 항체로, Mouse 및 Rat 시료에 반응. Western blot, ELISA, Immunoprecipitation에 사용 가능. 합성 펩타이드 면역원으로 제작되었으며, 고순도 Affinity chromatography 정제. 연구용으로만 사용.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| ELISA | 1:10,000 |
| Immunoprecipitation (IP) | 1:50–1:250 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide within amino acid region 100–150 on rat relaxin receptor 1 protein |
| Conjugate | Biotin |
| Form | Liquid |
| Concentration | 0.5–1.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | Proprietary buffer, pH 7.4–7.8, with 30% glycerol, 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Relaxins are endocrine and autocrine/paracrine hormones belonging to the insulin gene superfamily. In humans, there are three non-allelic relaxin genes: RLN1, RLN2, and RLN3, with RLN1 and RLN2 sharing high sequence homology.
The encoded protein is synthesized as a single-chain polypeptide, but the active form consists of an A chain and a B chain linked by disulfide bonds. Relaxin is produced by the ovary and acts on the reproductive system to ripen the cervix, elongate the pubic symphysis, and inhibit uterine contraction.
Additional roles include enhancing sperm motility, regulating blood pressure, controlling heart rate, and releasing oxytocin and vasopressin.
This gene has multiple polyadenylation sites and several alternatively spliced transcript variants whose full-length sequences are not yet known.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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