Thermo Fisher Scientific JAM-A (CD321) Polyclonal Antibody
JAM-A (CD321) 단백질을 인식하는 염소 유래 다클론 항체로, 인간 및 마우스에 반응합니다. Western blot 등 다양한 응용에 적합하며, 고순도 액상 형태로 제공됩니다. 세포 접착 및 상피 장벽 연구에 유용합니다.
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Applications
- Western Blot (WB): 0.3–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide sequence (QPSARSEGEFKQTS) corresponding to the C-terminus amino acids of F11R (aa 282–295) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_10986745 |
Product Specific Information
This antibody is predicted to react with canine, mouse, porcine, and rat based on sequence homology.
Tested in Peptide ELISA: antibody detection limit dilution 2,000.
Target Information
CD321 (F11R, JAM-1, JAM-A) is a cell-surface adhesion molecule belonging to the Ig superfamily of receptors. It is a 32–41 kD glycoprotein with two extracellular Ig-like domains, a transmembrane region, and a short cytosolic tail.
The protein forms homodimers at the membrane and associates with other membrane proteins, including integrins.
CD321 is expressed on leukocytes, platelets, erythrocytes, stem cells, epithelial and endothelial cells, and mediates cell-cell contact.
It is located near epithelial tight junction components such as ZO-1 and occludin and plays roles in maintaining epithelial and endothelial barriers, hematopoiesis, angiogenesis, and tumor proliferation, invasion, and metastasis.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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