Thermo Fisher Scientific JAM2 Polyclonal Antibody
JAM2 단백질을 인식하는 염소 유래 다클론 항체로, Western blot에 적합합니다. 인간 시료에 반응하며, 서열 상 유사성으로 소, 개, 마우스, 랫에서도 예측 반응합니다. 액상 형태로 0.5 mg/mL 농도이며, TBS(pH 7.3)와 0.5% BSA 포함. 연구용 전용 제품입니다.
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Applications
Western Blot (WB)
- Tested Dilution: 0.5–1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide sequence (QRKGYFSKETSFQ) corresponding to internal amino acids of JAM2 (aa 262–275) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_10981331 |
Product Specific Information
- This antibody is predicted to react with bovine, canine, mouse, and rat based on sequence homology.
- Tested in Peptide ELISA: antibody detection limit dilution 4,000.
Target Information
Tight junctions are cell-to-cell adhesion structures in epithelial or endothelial sheets that form continuous seals around cells, acting as physical barriers to regulate solute and water passage through the paracellular space.
The JAM2 protein, a member of the immunoglobulin superfamily, is localized in tight junctions between high endothelial cells. It functions as an adhesive ligand interacting with various immune cell types and may play a role in lymphocyte homing to secondary lymphoid organs.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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