Thermo Fisher Scientific RGS1 Polyclonal Antibody

Thermo Fisher Scientific RGS1 Polyclonal Antibody

Applications

• Western Blot (WB): 1–3 µg/mL

Product Specifications

Product Specific Information

• Suggested positive control: Jurkat cell lysate.

Target Information

This gene encodes a member of the regulator of G-protein signaling family. This protein is located on the cytosolic side of the plasma membrane and contains a conserved, 120 amino acid motif called the RGS domain.
The protein attenuates the signaling activity of G-proteins by binding to activated, GTP-bound G alpha subunits and acting as a GTPase activating protein (GAP), increasing the rate of conversion of GTP to GDP.
This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.