Thermo Fisher Scientific QPRT Monoclonal Antibody (OTI4B4), TrueMAB

Applications and Tested Dilution

Product Specifications

Product Specific Information

For reconstitution, add 100 µL of distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).

Target Information

The QPRT gene encodes a key enzyme involved in the catabolism of quinolinate, an intermediate in the tryptophan–nicotinamide adenine dinucleotide pathway.
Quinolinate acts as a potent endogenous excitotoxin to neurons, and elevated levels in the brain have been associated with neurodegenerative disorders such as epilepsy, Alzheimer’s disease, and Huntington’s disease.
Alternative splicing results in multiple transcript variants.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.