Thermo Fisher Scientific CD41 Recombinant Mouse Monoclonal Antibody (BAG 75E5)
인간 CD41 항원을 인식하는 재조합 마우스 단클론 항체로, IHC 등 다양한 연구용에 적합합니다. HEK293 세포에서 발현되었으며, Protein A로 정제된 액상 형태입니다. 단기 4°C, 장기 -20°C 보관 권장.
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Applications
- Immunohistochemistry (IHC): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | BAG 75E5 |
| Immunogen | This antibody was raised by immunising mice with human CD41. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_3074704 |
Product Specific Information
Specificity: This antibody recognises CD41 antigen.
Target Information
CD41 (platelet glycoprotein IIb, ITGA2B) consists of two subunits (120 kDa α and 23 kDa β) that interact with CD61 in the presence of calcium to form a functional adhesive protein receptor. CD41 participates in blood coagulation by mediating platelet aggregation. Upon vascular injury, CD41 binds to von Willebrand factor, fibrinogen, fibronectin, and vitronectin. It is mainly expressed on the megakaryocyte-platelet lineage and is also found during early hematopoietic differentiation. CD41 dysfunction is associated with Glanzmann Thrombasthenia and Platelet type-16 bleeding disorder.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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