Thermo Fisher Scientific IFNAR1 Polyclonal Antibody
Human IFNAR1 단백질을 인식하는 goat polyclonal 항체로, Western blot과 Flow cytometry에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, PBS 용액 상태로 제공됩니다. 단기 4°C, 장기 -20°C 보관 권장.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 0.1–0.2 µg/mL | - |
| Flow Cytometry (Flow) | 3–10 µg/test | - |
| Inhibition Assays (IA) | - | View 1 publication |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Purified, recombinant human interferon-alpha/beta receptor 1 (IFNAR1) extracellular domain expressed in insect Sf cells |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_794532 |
Product Specific Information
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Interferons are widely used therapeutic agents because of their anti-tumor and antiviral effects and their modulatory effects on the immune system (Biron, 2001; Kirkwood, 2002). These cytokines exert their effects by binding to the Type I Interferon Receptor (IFNAR1). Downregulation of this receptor plays a key role in determining the magnitude and duration of cytokine signaling, which is thought to be influenced by phosphorylation of Serine 535 and 539 in IFNAR1 (Kumar et al., 2003).
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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