Thermo Fisher Scientific SRC Polyclonal Antibody
제브라피쉬 SRC 단백질을 인식하는 Rabbit Polyclonal 항체로 Western blot에 최적화됨. 고순도 Protein G 정제, 액상 형태로 제공되며 PBS/glycerol buffer에 안정화. 세포 성장과 신호전달 연구용으로 적합.
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Applications
- Western Blot (WB)
Tested Dilution: 1:500–1:5,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Zebrafish |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Zebrafish Proto-oncogene tyrosine-protein kinase Src protein (2–146aa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2.464 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.03% ProClin 300 |
| Storage Conditions | -20°C or -80°C if preferred |
| Shipping Conditions | Wet ice |
| RRID | AB_2902163 |
Product Specific Information
This antibody has been tested in direct-ELISA.
Target Information
SRC is a cytoplasmic tyrosine kinase and proto-oncogene involved in the regulation of embryonic development and cell growth. It associates with various cell surface receptors to facilitate signal transduction and plays roles in cytoskeletal organization, cell cycle regulation, and apoptosis.
In humans, the SRC gene is located on chromosome 20. Its activity is regulated by phosphorylation at two tyrosine residues (Tyr416 and Tyr527), which have opposing effects on enzyme activity. Mutations in SRC may contribute to malignant progression of colon cancer. Two transcript variants encoding the same SRC protein have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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