Thermo Fisher Scientific Thrombomodulin Recombinant Rabbit Monoclonal Antibody (BLR253L)
Thrombomodulin 표적의 재조합 Rabbit Monoclonal Antibody로 다양한 면역실험(WB, IHC, ICC, Flow, IP)에 사용 가능. Human 반응성, HEK293F 발현, 고순도 정제, 액상 형태. 연구용으로 혈관 관련 단백질 분석에 적합.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
| Flow Cytometry (Flow) | 0.25 µL/10⁶ cells |
| Immunoprecipitation (IP) | 12 µL/mg of lysate |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293F |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | BLR253L |
| Immunogen | Recombinant protein representing the extracellular domain of Human Thrombomodulin (residues 17–515) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 500 µg/mL |
| Purification | Purified |
| Storage Buffer | BBS, pH 8.2, with 0.1% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Immunohistochemistry: Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
Target Information
Thrombomodulin (TM), also known as Fetomodulin (FM), endothelial anticoagulant protein, or glycoprotein P112, is a membrane glycoprotein expressed on endothelial cells. It contains six epidermal growth factor (EGF)-like domains and a lectin-like amino terminal domain. TM accelerates activation of protein C, contributing to thrombo-resistance and reducing clot formation on endothelial surfaces. Immunohistochemical staining for TM is used in the study of vascular tumors, meningiomas, and choriocarcinomas.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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