Thermo Fisher Scientific PD L1 (CD274) Monoclonal Antibody (OTI11G4)
PD-L1(CD274)에 특이적인 단클론 항체로, Western blot과 유세포분석에 적합. 인간 시료에 반응하며, HEK293T 세포에서 발현된 재조합 단백질을 면역원으로 사용. 액상 형태, 1 mg/mL 농도, 친화 크로마토그래피로 정제. 연구용으로만 사용 가능.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500 |
| Flow Cytometry (Flow) | 1:50–1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI11G4 |
| Immunogen | Full-length human recombinant protein of human CD274 (NP_054862) produced in HEK293T cells |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Programmed death receptor ligand 1 (PD-L1, also called B7-H1) is a B7 family member that binds to the receptor PD-1, which negatively regulates T-cell receptor (TCR) signaling. Upon binding PD-1, PD-L1 decreases TCR-mediated proliferation and cytokine production. PD-L1 expression is abundant in many murine and human cancers and can be upregulated upon IFN-gamma stimulation, suggesting its role in tumor immune evasion.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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