Thermo Fisher Scientific PD L1 (CD274) Monoclonal Antibody (OTI9A5)
인간 PD-L1(CD274)을 인식하는 Mouse IgG2b 단일클론 항체로, Western blot 및 유세포 분석에 적합. 고순도 친화 크로마토그래피 정제, 액상 형태로 제공. 암 면역회피 연구에 활용 가능. 연구용으로만 사용.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500
Flow Cytometry (Flow)
- Tested Dilution: 1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI9A5 |
| Immunogen | Full length human recombinant protein of human CD274 (NP_054862) produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Target Information
Programmed death receptor ligand 1 (PD-L1, also called B7-H1) is a member of the B7 family. PD-L1 binds to the receptor PD-1, which negatively regulates T-cell receptor (TCR) signaling. Upon receptor binding, PD-L1 decreases TCR-mediated proliferation and cytokine production. PD-L1 expression is abundant in many murine and human cancers and can be up-regulated by IFN-gamma stimulation. This suggests PD-L1 plays a critical role in tumor immune evasion.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지: TA812586_PD-L1_CD274_Q9NZQ7-1_House_mouse.svg)
(이미지: TA812586_PD-L1_CD274_Q9NZQ7-1_House_mouse_PDP.jpeg)
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