Thermo Fisher Scientific CDK5 Polyclonal Antibody
CDK5 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, WB, IHC, ELISA, IP 등 다양한 응용에 사용 가능. 인간, 생쥐, 랫트 시료 반응. 고농도(85 mg/mL) 액상 형태로 -20°C 보관. 연구용 전용 제품.
- 카탈로그번호
- 100-401-163
- 판매단위
- pk
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:5,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| ELISA | 1:5,000–1:20,000 |
| Immunoprecipitation (IP) | 1:500–1:5,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | CDK5 (p31) peptide corresponding to the C-terminus of the human protein conjugated to Keyhole Limpet Hemocyanin (KLH) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 85 mg/mL |
| Storage Buffer | Whole serum |
| Contains | 0.01% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Store vial at -20°C prior to opening.
- Aliquot contents and freeze at -20°C or below for extended storage.
- Avoid cycles of freezing and thawing.
- Centrifuge if not completely clear after standing at room temperature.
- Stable for several weeks at 4°C as an undiluted liquid.
- Dilute only prior to immediate use.
Antiserum specifically reacts with a 35 kDa CDK5 (p31) protein from human, rat, and mouse tissue.
No reaction observed against other related cyclin-dependent kinases.
Cross-reactivity with CDK5 (p31) from other species may also occur.
Target Information
CDK5 is a member of the Cyclin-Dependent Kinase family, abundant in the mammalian brain.
The active form, also known as neuronal cdc2-like kinase, is a heterodimer of CDK5 and a 25 kDa protein derived from a 35 kDa neuron-specific precursor.
CDK5 plays a crucial role in neuronal migration during CNS development and phosphorylates diverse substrates, regulating processes such as adhesion, motility, synaptic plasticity, and drug addiction.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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