Thermo Fisher Scientific BCL10 Monoclonal Antibody (OTI1B3), TrueMAB
BCL10 단백질을 인식하는 Mouse IgG1 단일클론 항체로, Western blot 및 IHC(P) 적용 가능. HEK293T 세포에서 생산된 full-length human recombinant BCL10을 면역원으로 사용. 무보존제, 동결건조 형태로 제공되며 연구용으로 적합.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:150
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1B3 |
| Immunogen | Full length human recombinant protein of human BCL10 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step.
Recommended: Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL (Product #89882)
Target Information
BCL-10 is an N-terminal CARD (Caspase Recruitment Domain) containing protein involved in the adaptive immune response.
It promotes apoptosis, pro-caspase-9 maturation, and NF-kappa-B activation via NIK and IKK.
BCL-10 functions as an adapter protein linking the TNFR1-TRADD-RIP complex to the NIK-IKK-IKAP complex and serves as a substrate for MALT1.
Mutations in the BCL10 gene may lead to Immunodeficiency 37 or mucosa-associated lymphoid type lymphoma.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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