Thermo Fisher Scientific AKR1B10 Polyclonal Antibody
AKR1B10 단백질을 인식하는 Thermo Fisher Scientific의 염소 유래 폴리클로날 항체. Western blot에 최적화되어 있으며 인간 시료에 반응. 합성 펩타이드 면역원 사용, 고순도 액상 형태. 0.5 mg/mL 농도로 제공되며 -20°C에서 보관. 연구용으로만 사용 가능.
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Thermo Fisher Scientific AKR1B10 Polyclonal Antibody
Applications
- Western Blot (WB): 0.03–0.1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide sequence (QSSHLEDYPFDAE) corresponding to the C-terminus amino acids of AKR1B10 (aa 303–313) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_10979307 |
Product Specific Information
This antibody is tested in Peptide ELISA: antibody detection limit dilution 8,000.
Target Information
AKR1B10 is a 316 amino acid protein that catalyzes efficient reduction of aliphatic and aromatic aldehydes. It is the first cytosolic NADP(H)-dependent retinal reductase described in humans and is characterized by a novel NADP binding motif.
Due to its ability to convert glucose to sorbitol, AKR1B10 may play a role in the development of secondary diabetic complications.
It is abundantly expressed in adrenal gland, small intestine, and colon, with lower levels in liver, thymus, prostate, testis, and skeletal muscle. Its expression levels are upregulated in certain cancers such as hepatocellular carcinoma.
Usage Note
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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