Thermo Fisher Scientific SENP6 Polyclonal Antibody
SENP6 단백질을 인식하는 Thermo Fisher Scientific의 Goat Polyclonal Antibody로, ICC/IF 및 Flow Cytometry에 사용 가능. 인간 시료 반응성, 마우스 및 랫트 교차 반응 예상. 고순도, 액상 형태로 연구용에 적합.
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Applications
Immunocytochemistry (ICC/IF)
- Tested Dilution: 10 µg/mL
Flow Cytometry (Flow)
- Tested Dilution: 10 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide sequence (KPKYEPNPHYHEN) corresponding to the internal amino acids of SENP6 (aa 778–791) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_10977937 |
Product Specific Information
- This antibody is predicted to react with mouse and rat based on sequence homology.
- Tested in Peptide ELISA: antibody detection limit dilution 1:32,000.
Target Information
Ubiquitin-like molecules, such as SUMO1, are structurally related to ubiquitin and can be ligated to target proteins similarly. Unlike ubiquitin, SUMO1 modification does not lead to degradation of modified proteins. SUMO1 is involved in targeting RANGAP1 to the nuclear pore complex and stabilizing I-kappa-B-alpha against proteasomal degradation.
UBLs are synthesized as precursors and require processing by UBL-specific proteases, such as SENP6, before conjugation. SENP6 also exhibits isopeptidase activity for deconjugation of SUMO-conjugated substrates.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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