Thermo Fisher Scientific C5a2, Complement C5a Receptor 2 Polyclonal Antibody
Rabbit polyclonal antibody targeting human C5a Receptor 2 (C5AR2). Validated for WB and ICC/IF applications. High specificity and sensitivity with antigen affinity purification. Supplied as liquid in PBS buffer with sodium azide preservative. For resea...
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- 7TM0033N
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:1,000 | View 1 publication |
| Immunocytochemistry (ICC/IF) | 1:200 | View 1 publication |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide corresponding to the carboxyl-terminal tail of human C5a2. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Dulbecco’s PBS, pH 7.4 |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C for short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice (domestic); Dry ice (international) |
Target Information
C5AR2 (Complement C5a Receptor 2) is an orphan member of the anaphylatoxin receptor family. It is a seven-transmembrane G-protein-coupled receptor featuring an N-terminal N-glycosylation site, conserved cysteines, and potential C-terminal phosphorylation sites.
C5AR2 binds to C5a and C5a-des-Arg, acting as a regulated scavenger receptor with a negative modulatory effect on C5aR-mediated inflammation.
Expression has been observed in neutrophils, macrophages, mast cells, dendritic cells, brain, lung, heart, kidney, liver, ovary, and testis.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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