Thermo Fisher Scientific Phospho-Gastric Inhibitory Polypeptide Receptor (Thr442, Ser443) Polyclonal Antibody
인간 GIPR 단백질의 Thr442/Ser443 인산화 부위를 인식하는 폴리클로날 항체. Western blot 검증 완료. 항원 친화 크로마토그래피로 정제된 고순도 제품. 연구용으로 인슐린 분비 관련 신호전달 연구에 적합.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic phosphopeptide derived from human GIPR around the phosphorylation site of Thr442/Ser443 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Dulbecco’s PBS, pH 7.4 |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice (domestic); Dry ice (international) |
Target Information
GIPR encodes a G-protein coupled receptor for gastric inhibitory polypeptide (GIP), originally identified as an activity in gut extracts that inhibited gastric acid secretion and gastrin release. It was later shown to stimulate insulin release in the presence of elevated glucose. Mice lacking this gene exhibit higher blood glucose levels with impaired initial insulin response after oral glucose load. Defects in this gene may contribute to the pathogenesis of diabetes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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