Thermo Fisher Scientific Phospho-Gastric Inhibitory Polypeptide Receptor (Ser433, Ser435) Polyclonal Antibody
인산화 GIP 수용체(Ser433, Ser435)를 인식하는 Rabbit Polyclonal 항체로, Western blot에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, 휴먼 시료에 반응합니다. 액상 형태로 제공되며, 단기 4°C, 장기 -20°C 보관이 권장됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic phosphopeptide derived from human GIPR around the phosphorylation site of Ser433/Ser435. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Dulbecco’s PBS, pH 7.4 |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice (domestic); Dry ice (international) |
Target Information
GIPR (Gastric Inhibitory Polypeptide Receptor) encodes a G-protein coupled receptor for gastric inhibitory polypeptide (GIP).
GIP was first identified as an activity in gut extracts that inhibited gastric acid secretion and gastrin release, but later found to stimulate insulin release in the presence of elevated glucose.
Mice lacking this gene show higher blood glucose levels with impaired initial insulin response after oral glucose load.
Defects in this gene may contribute to the pathogenesis of diabetes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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