Thermo Fisher Scientific SMC1A Monoclonal Antibody (OTI3G4), TrueMAB
SMC1A 단백질을 인식하는 마우스 단클론 항체로 Western blot 및 IHC(P) 분석에 적합. 인간, 마우스, 랫트에 반응하며, 동결건조 형태로 제공. 염석 크로마토그래피로 정제되어 높은 순도 보장. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3G4 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 889–1016 of human SMC1A produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
Structural Maintenance of Chromosomes (SMC) family proteins play essential roles in nuclear processes requiring chromosomal structural changes, such as mitotic chromosome organization, DNA recombination, repair, and transcriptional repression.
SMC1 and SMC3 form a heterodimeric complex critical for metaphase progression and sister chromatid cohesion.
Mutations in the SMC1A gene are associated with Cornelia de Lange syndrome 2, highlighting its role in mitotic chromosome dynamics.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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