Thermo Fisher Scientific Syntaxin 1 Chimeric Recombinant Rabbit Monoclonal Antibody (SP6)
Syntaxin 1 단백질을 인식하는 재조합 토끼 단클론 항체로, Western blot 및 IHC에 사용 가능. 다양한 종에서 반응하며, HEK293 세포에서 발현. 단백질 A로 정제된 액상 형태로 제공되며, 신경계 시냅스 소포 연구에 적합.
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Applications
Western Blot (WB)
- Tested Dilution: Assay-dependent
Immunohistochemistry (IHC)
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Bovine, Dog, Guinea pig, Hamster, Human, Pig, Rabbit, Rat |
| Host / Isotype | Rabbit / IgG, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | SP6 |
| Immunogen | Synaptic vesicle-containing fractions immunoprecipitated from human brain homogenates |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_3074328 |
Product Specific Information
- Specificity: This antibody binds to native and denatured syntaxin.
Target Information
Syntaxin 1 is a member of the syntaxin superfamily. Syntaxins are nervous system-specific proteins implicated in the docking of synaptic vesicles with the presynaptic plasma membrane.
They possess a single C-terminal transmembrane domain, a SNARE (Soluble NSF Attachment protein REceptor) domain (H3), and an N-terminal regulatory domain (Habc).
Syntaxins bind synaptotagmin in a calcium-dependent manner and interact with voltage-dependent calcium and potassium channels via the C-terminal H3 domain.
This gene product is a key molecule in ion channel regulation and synaptic exocytosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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