Thermo Fisher Scientific Abl2 Recombinant Rabbit Monoclonal Antibody (ARC2200)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Expression System

HEK293 cells

Class

Recombinant Monoclonal

Type

Antibody

Clone

ARC2200

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 500-600 of human ABL2 (P42684) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:Abl2,uniProtId:P42684-1,ncbiNodeId:9606,antigenRange:500-600,antigenLength:1182,antigenImageFileName:MA5-37932_Abl2_P42684-1_Rabbit.svg,antigenImageFileNamePDP:MA5-37932_Abl2_P42684-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.47 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.3, with 0.05% BSA, 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2897852

Product Specific Information

Positive Samples: HeLa, 293T, U-87MG, Rat testis

Immunogen sequence: KGYRMEQPEG CPPKVYELMR ACWKWSPADR PSFAETHQAF ETMFHDSSIS EEVAEELGRA ASSSSVVPYL PRLPILPSKT RTLKKQVENK ENIEGAQDAT E

Target Information

ABL2 (Arg) is an Abl-related non-receptor protein tyrosine kinase that links cell surface receptors to cell proliferation and/or cytoskeletal reorganization. Abl2 encodes a member of the Abelson family of nonreceptor tyrosine protein kinase. The protein is highly similar to the ABL1 protein, including the tyrosine kinase, SH2 and SH3 domains, and has a role in cytoskeletal rearrangements by its C-terminal F-actin- and microtubule-binding sequences. Abl2 is expressed in both normal and tumor cells, and is involved in translocation with the ETV6 gene in leukemia. Multiple alternatively spliced transcript variants encoding different protein isoforms have been found for this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.