Thermo Fisher Scientific Abl2 Recombinant Rabbit Monoclonal Antibody (ARC2200)
ABL2 단백질을 인식하는 토끼 단클론 항체로, Western blot 및 ELISA에 적합합니다. 인간, 마우스, 랫트 시료에 반응하며, HEK293 세포에서 발현된 재조합 항체입니다. 높은 특이성과 안정적인 신호로 세포 신호전달 연구에 유용합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | ARC2200 |
| Immunogen | A synthetic peptide corresponding to a sequence within amino acids 500–600 of human ABL2 (P42684) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.47 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 0.05% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2897852 |
Product Specific Information
- Positive Samples: HeLa, 293T, U-87MG, Rat testis
- Immunogen sequence:
KGYRMEQPEG CPPKVYELMR ACWKWSPADR PSFAETHQAF ETMFHDSSIS EEVAEELGRA ASSSSVVPYL PRLPILPSKT RTLKKQVENK ENIEGAQDAT E
Target Information
ABL2 (Arg) is an Abl-related non-receptor protein tyrosine kinase that links cell surface receptors to cell proliferation and/or cytoskeletal reorganization.
Abl2 encodes a member of the Abelson family of nonreceptor tyrosine protein kinases. The protein is highly similar to the ABL1 protein, including the tyrosine kinase, SH2, and SH3 domains, and has a role in cytoskeletal rearrangements by its C-terminal F-actin- and microtubule-binding sequences.
Abl2 is expressed in both normal and tumor cells, and is involved in translocation with the ETV6 gene in leukemia. Multiple alternatively spliced transcript variants encoding different protein isoforms have been found for this gene.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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