Thermo Fisher Scientific FLAP Recombinant Rabbit Monoclonal Antibody (ARC2204)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000-1:2,000

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Expression System

HEK293 cells

Class

Recombinant Monoclonal

Type

Antibody

Clone

ARC2204

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 62-161 of human FLAP (P20292) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:FLAP,uniProtId:P20292-1,ncbiNodeId:9606,antigenRange:62-161,antigenLength:161,antigenImageFileName:MA5-37933_FLAP_P20292-1_Rabbit.svg,antigenImageFileNamePDP:MA5-37933_FLAP_P20292-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.58 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.3, with 0.05% BSA, 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2897853

Product Specific Information

Positive Samples: A-549, THP-1, U-937

Immunogen sequence: DAYPTFLAVL WSAGLLCSQV PAAFAGLMYL FVRQKYFVGY LGERTQSTPG YIFGKRIILF LFLMSVAGIF NYYLIFFFGS DFENYIKTIS TTISPLLLIP

Target Information

ALOX5AP is a protein which, with 5-lipoxygenase, is required for leukotriene synthesis. Leukotrienes are arachidonic acid metabolites which have been implicated in various types of inflammatory responses, including asthma, arthritis and psoriasis. This protein localizes to the plasma membrane. Inhibitors of its function impede translocation of 5-lipoxygenase from the cytoplasm to the cell membrane and inhibit 5-lipoxygenase activation.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.