Thermo Fisher Scientific Phospho-4EBP1 (Thr37, Thr46) Recombinant Rabbit Monoclonal Antibody (4EB1T37T46-A5), APC
Phospho-4EBP1 (Thr37, Thr46) 인산화 부위를 인식하는 재조합 토끼 단클론 항체로, APC 형광 표지되어 있습니다. 인간, 마우스, 랫트 시료에 반응하며, 유세포분석(Flow Cytometry)에 적합합니다. 단백질 번역 조절 관련 연구에 활용됩니다.
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Applications
- Flow Cytometry (Flow): 5 µL / 1×10⁶ cells
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 4EB1T37T46-A5 |
| Immunogen | A synthetic phospho-peptide corresponding to residues surrounding Thr37/46 of human phospho 4E-BP1 |
| Conjugate | APC |
| Excitation / Emission Max | 651 / 660 nm |
| Form | Liquid |
| Purification | Protein A/G |
| Storage buffer | PBS with 0.20% BSA |
| Contains | 0.09% sodium azide |
| Storage conditions | 4°C |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2897178 |
Additional Formats
Target Information
This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5′ end of mRNAs. Interaction with eIF4E inhibits complex assembly and represses translation. Phosphorylation in response to signals such as UV irradiation or insulin causes dissociation from eIF4E and activation of mRNA translation.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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