Thermo Fisher Scientific CBX6 Polyclonal Antibody
CBX6 단백질을 인식하는 토끼 폴리클로날 항체로, Western blot 및 IHC(P)에서 검증됨. 인간, 마우스, 랫트 시료에 반응. 항원 친화 크로마토그래피로 정제되었으며, 고순도(>95%) 보유. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 1–50 of human CBX6 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2553388 |
Product Specific Information
- Detects endogenous CBX6 protein at a molecular weight of approximately 44 kDa.
- Purity: >95% by SDS-PAGE.
Target Information
Polycomb group (PcG) proteins form multiprotein complexes that regulate expression patterns of developmental and cell proliferation genes.
CBX6 (chromobox protein homolog 6) is a 412 amino acid protein that is a component of the chromatin-associated PcG complex.
Through interaction with PcG, CBX6 modifies chromatin and maintains the transcriptionally repressive state of genes.
Members of the chromobox domain protein family are characterized by the presence of a 37 amino acid chromobox (CHRomatin Organization MOdifier) domain, which plays a mechanistic role in targeting chromodomain proteins to specific nuclear regions.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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