Thermo Fisher Scientific PCSK9 Monoclonal Antibody (OTI8E10), TrueMAB
인간 PCSK9 단백질(aa 153-692)을 항원으로 제작된 Mouse IgG1 단클론 항체. Western blot에 적합하며 carrier-free 형태로 제공. 1 mg/mL 농도의 동결건조 제품으로, 재구성 후 실험 및 결합 실험에 활용 가능.
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Applications
- Western Blot (WB)
Tested Dilution: 1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI8E10 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 153–692 of human PCSK9 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
PCSK9 (Proprotein Convertase Subtilisin/Kexin Type 9) belongs to the proteinase K subfamily of the secretory subtilase family.
It is synthesized as a soluble zymogen and undergoes autocatalytic intramolecular processing in the endoplasmic reticulum.
PCSK9 plays a crucial role in cholesterol homeostasis and may contribute to cortical neuron differentiation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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