Thermo Fisher Scientific GSK3B Monoclonal Antibody (21A)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

View 1 publication 1 publication

Immunohistochemistry (IHC)

Assay-dependent

-

Flow Cytometry (Flow)

Assay-dependent

-

ELISA (ELISA)

1:1,000

-

Immunoprecipitation (IP)

5-10 µg

-

Product Specifications

Species Reactivity

Human, Rat, Xenopus

Published species

Rat

Host/Isotype

Mouse / IgG2a

Class

Monoclonal

Type

Antibody

Clone

21A

Immunogen

Purified recombinant Xenopus laevis protein.

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein G

Storage buffer

PBS, pH 7.2

Contains

0.01% sodium azide

Storage conditions

4°C short term, -80°C long term

RRID

AB_1074718

Product Specific Information

MA1-7621 detects GSK3 Beta from human, rat, and Xenopus laevis samples.

MA1-7621 has been successfully used in ELISA, Western blot, Flow cytometry, Immunoprecipitation and Immunohistochemistry procedures.

The MA1-7621 immunogen is a purified recombinant Xenopus laevis protein.

Store at 4ºC short term. For extended storage, keep at -80ºC.

Target Information

GSK3B is a proline-directed serine/threonine protein kinase involved in energy metabolism, neuronal cell development and body pattern formation. It is a negative regulator of glucose homeostasis and is involved in energy metabolism, inflammation, ER-stress, mitochondrial dysfunction, and apoptotic pathways. GSK3B is a critical component of the Wnt/beta-catenin signaling pathway, and its activity results in the inhibition of Wnt signaling by mediating the degradation of beta-catenin. GSK3B is also involved in the Hedgehog, Notch, and insulin signaling pathways.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.