Thermo Fisher Scientific Cytochrome P450 Reductase Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

0.5 µg/mL

-

Product Specifications

Species Reactivity

Dog, Guinea pig, Hamster, Human, Mouse, Non-human primate, Sheep, Pig, Rabbit, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Purified rat liver NADPH-Cytochrome P450 reductase. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:Cytochrome P450 Reductase,uniProtId:P00388-1,ncbiNodeId:10114,antigenRange:1-678,antigenLength:678,antigenImageFileName:PA1-29792_Cytochrome_P450_Reductase_P00388-1_Rabbit.svg,antigenImageFileNamePDP:PA1-29792_Cytochrome_P450_Reductase_P00388-1_Rabbit_PDP.jpeg,sortOrder:2}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein A

Storage buffer

PBS with 50% glycerol

Contains

0.09% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2252579

Product Specific Information

Suggested positive controls for this product are rat liver, NADPH, cytochrome, P450 and reductase protein.

Target Information

This gene encodes an endoplasmic reticulum membrane oxidoreductase with an FAD-binding domain and a flavodoxin-like domain. The protein binds two cofactors, FAD and FMN, which allow it to donate electrons directly from NADPH to all microsomal P450 enzymes. Mutations in this gene have been associated with various diseases, including apparent combined P450C17 and P450C21 deficiency, amenorrhea and disordered steroidogenesis, congenital adrenal hyperplasia and Antley-Bixler syndrome.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.