Thermo Fisher Scientific Phospho-4EBP1 (Thr37, Thr46) Polyclonal Antibody
Western blot에 최적화된 rabbit polyclonal antibody로, 4EBP1의 Thr37 및 Thr46 인산화를 특이적으로 인식합니다. Human, Mouse, Rat, Non-human primate 시료에 반응하며, 항원 친화 크로마토그래피로 정제되었습니다. 연구용으로만 사용 가능합니다.
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- PA517728
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- pk
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Non-human primate, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic phosphopeptide corresponding to residues surrounding pThr37 and pThr46 of mouse 4E-BP1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 219 µg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.01M HEPES, pH 7.5, with 0.15M NaCl, 100 µg/mL BSA, 50% glycerol |
| Contains | No preservative |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_10988130 |
Product Specific Information
It is not recommended to aliquot this antibody.
Target Information
This gene encodes a member of a family of translation repressor proteins that directly interact with eukaryotic translation initiation factor 4E (eIF4E). This interaction inhibits the assembly of the translation initiation complex and represses translation. Phosphorylation of this protein at Thr37 and Thr46 in response to various stimuli (such as UV irradiation or insulin signaling) leads to its dissociation from eIF4E and activation of mRNA translation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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