Thermo Fisher Scientific Phospho-SHP2 (Tyr542) Polyclonal Antibody
Phospho-SHP2 (Tyr542) 폴리클로날 항체로 SHP-2 단백질의 인산화 형태를 검출. Western blot 및 immunoprecipitation에 적합. Rabbit IgG 호스트로 제조된 비결합 액상 항체. 항원 친화 크로마토그래피로 정제되어 높은 특이성과 재현성 제공.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000
Immunoprecipitation (IP)
- Tested Dilution: 1:50
Miscellaneous PubMed (Misc)
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Chicken, Human, Mouse, Non-human primate, Rat, Xenopus |
| Published Species | Dog |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic phosphopeptide corresponding to residues surrounding pTyr542 of human SHP-2 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.01M HEPES, pH 7.5, with 0.15M NaCl, 100µg/mL BSA, 50% glycerol |
| Contains | No preservative |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_10981100 |
Product Specific Information
It is not recommended to aliquot this antibody.
Target Information
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are signaling molecules that regulate various cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains two tandem Src homology-2 domains that mediate substrate interactions. It is widely expressed and regulates diverse signaling events such as mitogenic activation, metabolic control, transcription regulation, and cell migration. Mutations in this gene are associated with Noonan syndrome and acute myeloid leukemia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일명: PA5-17721_SHP2_Q06124-2_Rabbit.svg, PA5-17721_SHP2_Q06124-2_Rabbit_PDP.jpeg)
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