Thermo Fisher Scientific Phospho-Acetyl-CoA Carboxylase (Ser79) Polyclonal Antibody
Phospho-Acetyl-CoA Carboxylase (Ser79) 폴리클로날 항체로, 인간·마우스·원숭이·랫트 반응성. WB, IHC, ICC, IP 등 다양한 응용 가능. 항원 친화 크로마토그래피로 정제된 고품질 항체. 지방산 합성 조절 단백질 연구에 적합.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:1,000 | View 2 publications |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:800 | - |
| Immunocytochemistry (ICC/IF) | 1:100 | - |
| Immunoprecipitation (IP) | 1:100 | - |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Non-human primate, Rat |
| Published Species | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic phosphopeptide corresponding to residues surrounding pSer79 of rat ACC |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 82.0 µg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.01M HEPES, pH 7.5, with 0.15M NaCl, 100 µg/mL BSA, 50% glycerol |
| Contains | No preservative |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_10981245 |
Product Specific Information
It is not recommended to aliquot this antibody.
Target Information
Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme that catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis.
There are two ACC forms, alpha and beta, encoded by distinct genes. ACC-alpha is highly enriched in lipogenic tissues.
The enzyme is regulated both long-term (transcriptional and translational levels) and short-term (phosphorylation/dephosphorylation of serine residues, allosteric regulation by citrate or palmitoyl-CoA).
Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(원본에 포함된 항원 관련 이미지 참조: PA5-17725_Acetyl-CoA_Carboxylase_P11497-1_Rabbit.svg, PA5-17725_Acetyl-CoA_Carboxylase_P11497-1_Rabbit_PDP.jpeg)
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