Thermo Fisher Scientific AGR2 Polyclonal Antibody
AGR2 단백질을 검출하기 위한 Rabbit Polyclonal 항체로, WB, IHC, ICC, IP 등 다양한 응용에 적합합니다. Human 및 Mouse에 반응하며, ProClin 300이 포함된 PBS 용액 형태로 제공됩니다. 암 연구 및 단백질 발현 분석에 유용합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:1,000 |
| Immunoprecipitation (IP) | 1:100–1:500 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein encompassing a sequence within the center region of human Anterior Gradient 2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.203 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 20% glycerol |
| Contains | 0.025% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2792776 |
Product Specific Information
- Keep as concentrated solution.
- Predicted reactivity: Mouse (93%), Rat (93%), Zebrafish (82%), Pig (96%), Rhesus Monkey (99%), Bovine (95%).
- Positive Control: MCF-7.
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
AGR2 (anterior gradient protein 2) and AGR3 are members of the anterior gradient homolog family. They are secreted cytoplasmic proteins involved in metastasis induction and p53 tumor suppressor inhibition. These proteins may serve as molecular markers and potential therapeutic targets for hormone-responsive breast tumors.
AGR2 is ubiquitously expressed and upregulated in prostate, breast, lung, renal, and endometrial carcinomas. Its expression is positively correlated with estrogen receptor (ER) levels and negatively correlated with epidermal growth factor receptor (EGFR) expression.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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