Thermo Fisher Scientific ERp72 Polyclonal Antibody, Alexa Fluor 647

Applications

Tested Dilution

Publications

Immunocytochemistry (ICC/IF)

1-10 µg/mL

-

Product Specifications

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Synthetic peptide corresponding to residues K(629) F I E E H A T K L S R T K E E L(645) of humna ERp72 if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:ERp72,uniProtId:P13667-1,ncbiNodeId:9606,antigenRange:630-645,antigenLength:645,antigenImageFileName:PA1-007-A647_ERp72_P13667-1_Rabbit.svg,antigenImageFileNamePDP:PA1-007-A647_ERp72_P13667-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Alexa Fluor™ 647 Alexa Fluor™ 647 Alexa Fluor™ 647

Excitation/Emission Max

650/671 nm View spectra

Form

Liquid

Concentration

1 mg/mL

Storage conditions

4° C, store in dark, DO NOT FREEZE!

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2662447

Product Specific Information

PA1007A647 detects ERp72 protein in human and mouse samples.

The PA1007A647 immunogen is a synthetic peptide corresponding to residues K(629) F I E E H A T K L S R T K E E L(645) of human ERp72. This peptide (Cat. # PEP-223) is available for use in neutralization and control experiments.

Target Information

ERp72 is an endoplasmic reticulum luminal protein that is both a stress protein and a member of the protein disulfide isomerase family of proteins. Sequence analysis of ERp72 shows that it shares sequence identity with PDI (protein disulphide isomerase) at three discrete regions, as well as containing the ER retention signal KEEL at its C-terminus. ERp72 is shown to have three copies of sequence believed to be CGHC-containing active sites, which are also found in PDI. These CGHC sites are critical sites that are involved in the protein disulphide isomerization process. These results suggest that ERp72 is a newly described member of the family of CGHC-containing proteins that functions as a molecular chaperone.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.