Thermo Fisher Scientific Ankyrin 2 Polyclonal Antibody
Mouse에서 반응하는 Rabbit Polyclonal Antibody로 Ankyrin 2(ANK2)에 특이적입니다. Western Blot 및 Immunohistochemistry에 사용 가능하며, 합성 펩타이드 항원을 기반으로 제작되었습니다. 연구용으로만 사용되며 장기 보관 시 -20°C에서 보관 권장.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:1,000–1:2,000 | - |
| Immunohistochemistry (IHC) | 1:1,000–1:2,000 | - |
| Miscellaneous PubMed (Misc) | - | View 1 publication |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide from internal region of mouse Ankyrin 2 (ANK2) conjugated to blue carrier protein |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
Specificity of this antibody: ANK3
Target Information
This gene encodes a member of the ankyrin family of proteins that link integral membrane proteins to the spectrin-actin cytoskeleton. Ankyrins are involved in cell motility, activation, proliferation, contact, and maintenance of specialized membrane domains.
Most ankyrins have three structural domains:
- Amino-terminal domain with ankyrin repeats
- Central spectrin binding domain
- Carboxy-terminal regulatory domain
The encoded protein is essential for targeting and stability of Na/Ca exchanger 1 in cardiomyocytes. Mutations in this gene cause long QT syndrome 4. Multiple transcript variants encoding different isoforms have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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