Thermo Fisher Scientific SERPINC1/AT3 (Antithrombin 3) Polyclonal Antibody
SERPINC1/AT3(안티트롬빈3)에 특이적인 Thermo Fisher Scientific의 폴리클로날 항체입니다. Western blot 및 IHC(P)에서 검증되었으며, 항원 친화 크로마토그래피로 정제되었습니다. 인간 및 생쥐 시료에 반응하며, 혈액 응고 조절 연구에 적합합니다.
- 카탈로그번호
- 630-130
- 판매단위
- pk
카탈로그
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.1–1 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 2–10 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide corresponding to the intra domain 160–175aa of human AT3 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS with proprietary stabilizer |
| Contains | 0.01% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Positive control: Human Plasma SERPINC1 protein
- Cellular location: Cytoplasmic
Target Information
The protein encoded by this gene is a plasma protease inhibitor and a member of the serpin superfamily. It inhibits thrombin and other activated serine proteases in the coagulation system, regulating the blood coagulation cascade. The protein contains two functional domains: a heparin-binding domain at the N-terminus and a reactive site domain at the C-terminus. Its inhibitory activity is enhanced by heparin. More than 120 mutations have been identified, many causing antithrombin-III deficiency.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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