Thermo Fisher Scientific SLA2 Monoclonal Antibody (OTI1F7), TrueMAB
SLA2 단백질을 인식하는 Mouse monoclonal antibody로 Western blot, IHC, Flow cytometry에 적합. Human 시료 반응성, Lyophilized 형태, PBS buffer에 보관. 연구용으로 T세포 수용체 신호 조절 연구에 활용 가능.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1F7 |
| Immunogen | Full length human recombinant protein of human SLA2 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
SLA2 is an adapter protein that negatively regulates T-cell receptor (TCR) signaling.
It inhibits T-cell antigen receptor-induced activation of nuclear factor of activated T-cells (NFAT).
SLA2 may function by linking signaling proteins such as ZAP70 with CBL, leading to CBL-dependent degradation of signaling proteins.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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