Thermo Fisher Scientific OTUB1 Monoclonal Antibody (OTI1A6), TrueMAB
OTUB1 단백질을 인식하는 Mouse monoclonal 항체로 Western blot 및 Flow cytometry에 적합. Human 시료에 반응하며, Lyophilized 형태로 제공. PBS 버퍼에 8% 트레할로스 포함, 보존제 무첨가. -20°C 보관 권장.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1A6 |
| Immunogen | Full length human recombinant OTUB1 protein produced in HEK293T cells |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Additional Formats
Product Specific Information
For reconstitution, add 100 µL distilled water to reach a final antibody concentration of about 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
The OTUB1 gene encodes a member of the OTU superfamily of predicted cysteine proteases.
This protein functions as a highly specific ubiquitin iso-peptidase that cleaves ubiquitin from branched poly-ubiquitin chains but not from ubiquitinated substrates.
It interacts with another ubiquitin protease and an E3 ubiquitin ligase that inhibits cytokine gene transcription in the immune system.
OTUB1 is proposed to act in specific ubiquitin-dependent pathways, possibly providing an editing function for polyubiquitin chain growth.
Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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