Thermo Fisher Scientific SLA2 Monoclonal Antibody (OTI2G3), TrueMAB
Human SLA2 단백질을 인식하는 Mouse IgG2b 단일클론 항체로, WB, IHC, ICC/IF, Flow Cytometry에 사용 가능. Lyophilized 형태로 제공되며, PBS buffer와 trehalose 함유. 연구용으로 TCR 신호 조절 관련 연구에 적합.
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Thermo Fisher Scientific SLA2 Monoclonal Antibody (OTI2G3), TrueMAB
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2G3 |
| Immunogen | Full-length human recombinant SLA2 protein produced in HEK293T cells |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of about 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
SLA2 is an adapter protein that negatively regulates T-cell receptor (TCR) signaling. It inhibits T-cell antigen-receptor induced activation of nuclear factor of activated T-cells (NFAT). SLA2 may link signaling proteins such as ZAP70 with CBL, leading to CBL-dependent degradation of signaling proteins.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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