Thermo Fisher Scientific PHF7 Monoclonal Antibody (OTI1F7), TrueMAB

Applications

Western Blot (WB)

• Tested Dilution: 1:500

Product Specifications

Product Specific Information

For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of about 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).

Target Information

Spermatogenesis is a complex process regulated by extracellular and intracellular factors as well as cellular interactions among interstitial cells of the testis, Sertoli cells, and germ cells. In the testis, this gene is expressed in Sertoli cells but not germ cells. However, it is not expressed in patients exhibiting spermatogenic arrest at the spermatocyte stage, which can result in oligospermia or azoospermia.
The proteins encoded by this gene contain plant homeodomain (PHD) finger domains, also known as leukemia associated protein (LAP) domains, involved in transcriptional regulation. This protein localizes to the nucleus of transfected cells and has been implicated in regulating spermatogenesis. Two protein isoforms are encoded by transcript variants of this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.