Thermo Fisher Scientific ASCC2 Monoclonal Antibody (OTI2D3), TrueMAB
ASCC2 단백질을 인식하는 Mouse IgG2b 형 단클론 항체로, Human 시료에 반응합니다. Western Blot 및 Immunocytochemistry에 적합하며, DNA 손상 복구 관련 연구에 활용됩니다. Lyophilized 형태로 제공되며, 고순도 Affinity chromatography 정제 제품입니다.
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Applications
- Western Blot (WB): 1:2,000
- Immunocytochemistry (ICC/IF): 1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2D3 |
| Immunogen | Full length human recombinant protein of human ASCC2 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
ASCC2 plays a role in DNA damage repair as a component of the ASCC complex. It recruits ASCC3 and ALKBH3 to sites of DNA damage by binding to polyubiquitinated proteins with Lys-63–linked polyubiquitin chains (PubMed:29144457).
It is part of the ASC-1 complex that enhances NF-kappa-B, SRF, and AP1 transactivation (PubMed:12077347).
[UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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